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Jens Juul Holst on the gut hormone discovery behind weight-loss drugs

Podcast: The Life Scientific · BBC Radio 4

Opublikowano: 2026-04-14

As recently as a few years ago, the idea of a self-administered injection that would deliver proven weight-loss results might have sounded fantastical. Today, these medications are a reality and a global phenomenon; hailed in many quarters as “miracle drugs" for their success in treating obesity and diabetes. They do this by replicating a gut hormone called GLP‑1, which tells the brain you’ve eaten enough and nudges the pancreas to release insulin; and this hormone was discovered and decoded thanks to years of work by today's guest. Jens Juul Holst is a Professor of Medica...