How Bitter Taste Receptors in Your Gut Can Instantly Kill Food Cravings - Episode 339

Podcast: Gladden Longevity Podcast · Gladden Longevity Podcast

Opublikowano: 2026-05-07

In this episode, Dr. Gladden and nutrition expert Sarah Kennedy discuss Calocurb, a natural extract that uses evolutionary biology to suppress appetite. The discovery focuses on bitter taste receptors (T2Rs) located throughout the gastrointestinal tract, which historically served as a protective mechanism to slow the consumption of potentially toxic substances. By using a specific New Zealand hop extract, Calocurb triggers these receptors to signal the brain that the body is full. This process stimulates the natural release of satiety hormones—GLP-1, CCK, and PYY—effectively quieting "hunger noise" and reducing caloric intake without the need for synthetic pharmaceuticals. <...