Antidepressant Tier List: Psychiatrists Rank Depression Medications for MDD

Podcast: Psychofarm Podcast · Psychiatry, Skepticism, and Integration.

Opublikowano: 2026-05-19

Psychiatrists rank antidepressants for major depressive disorder, including SSRIs like sertraline, escitalopram, fluoxetine, and paroxetine; SNRIs like venlafaxine and duloxetine; and atypical options like bupropion and mirtazapine. They also cover lithium, low-dose aripiprazole, trazodone, esketamine, stimulants, benzodiazepines, TCAs, and MAOIs, with emphasis on diagnosis, side effects, withdrawal, weight gain, sexual dysfunction, anxiety, insomnia, and why “which antidepressant is best” depends on the patient. What we cover * How the hosts set the rules for a tier list of antidepressants for major depressive disorder: one ranks by tolerability (especially avoiding weight gain) and then efficacy, the other goes...