PROPOFOL: THE DRUG YOU THINK YOU KNOW │ EP104

Podcast: Atomic Anesthesia · Rhea Temmermand, PhD, CRNA & Sachi Lord, MSN, CRNA

Opublikowano: 2026-07-28

Propofol, a cornerstone in anesthesia practice, functions as a positive allosteric modulator at the GABA-A receptor. This episode explores its receptor pharmacology, the mechanisms behind its dose-dependent clinical effects, and addresses common questions like propofol infusion syndrome and pain on injection. Receptor pharmacology and allosteric modulationPharmacokinetics and context-sensitive half-timeCardiac and respiratory effectsRisk and management of propofol infusion syndromeHandling egg allergy concernsStrategies to reduce pain on injection FREE RESOURCE FOR THIS EPISODE: GPCR Cheat Sheet — G-protein coupled receptors decoded for anesthesia. Head to atomicanesthesia.com/freebies/gpcr-cheat-sheet to grab it free. MORE FREE ST...