SGLT2i Therapy for Horses

Podcast: Conversations in Equine Science · Nancy McLean

Opublikowano: 2026-08-22

This episode reviews cases of steroid-induced laminitis and examines recent research and owner-reported experiences using SGLT2 inhibitors (most commonly ertugliflozin) as an off-label treatment for equine metabolic syndrome and hyperinsulinemia-associated laminitis. An online survey of 342 owners found most horses treated with SGLT2Is showed improved quality of life and reduced pain, with many horses spared from euthanasia; common initial side effects included increased drinking and urination, weight loss, and dullness, which were often dose-dependent or resolved over time. Key takeaways: SGLT2Is show promise as a rescue option for laminitis when combined with strict dietary...