Liquid Biopsy: Current Applications and Future Direction

Podcast: Weekly Neurology Deep Dive - A review of recent impactful publications in the field of Neurology · Amer Ghavanini

Opublikowano: 2026-09-13

This comprehensive review examines the evolution and clinical potential of liquid biopsy, a non-invasive diagnostic method that analyzes biomarkers within bodily fluids. The text classifies primary biomarkers such as circulating tumor DNA, intact tumor cells, and extracellular vesicles, while detailing the high-sensitivity technologies like digital PCR and next-generation sequencing used to detect them. In oncology, the authors highlight how these tools facilitate early cancer screening, the prediction of therapeutic responses, and the real-time monitoring of minimal residual disease or drug resistance. The scope extends beyond cancer to include applications in reproductive medicine, organ transplantation, and neurological disorders. Finally, the researchers ad...