LDL on Keto: What Happens When Ezetimibe Enters the Picture? | Dr. Josh Wageman, Dr. Laura Buchanan, and Dr. Matt Calkins - E460

Podcast: Low Carb MD Podcast · Dr. Brian Lenzkes, Dr. Tro

Opublikowano: 2026-09-21

A ketogenic diet can dramatically improve metabolic health while sending LDL-C through the roof. So what's actually happening? Dr. Josh Wageman and Dr. Laura Buchanan break down their new study, "Increased LDL-C reduction with ezetimibe in ketogenic diet-induced hypercholesterolemia." The results raise some fascinating questions. In 14 patients who developed very high LDL-C while following a ketogenic diet, ezetimibe cut median LDL-C from 254 to 127 mg/dL—a remarkable 53% reduction. Why was the response so much greater than what's typically seen with ezetimibe? Could altered cholesterol absorption help explain why some people experience dramatic LDL increases on keto? ...