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Podcast: STAT Stitch Deep Dive Podcast Beyond The Bedside · Regular Guy

Opublikowano: 2026-10-02

1. DM Classification & Core Diagnostics Type 1 DM: Autoimmune β-cell destruction (HLA-DR3/DR4) causing absolute insulin deficiency; presents abruptly with classic 3 Ps (polyuria, polydipsia, polyphagia), weight loss, and DKA risk[1][2].Type 2 DM: Insulin resistance combined with relative β-cell deficiency and inappropriate hepatic glucose production[3]. Onset is gradual[4].Diagnostic Criteria: A1C ≥6.5%, Fasting Plasma Glucose ≥126 mg/dL, 2-hr OGTT ≥200 mg/dL, or Random Glucose ≥200 mg/dL with classic symptoms[5]. Glycemic target A1C is