CC CJM | CKD v AKI

Podcast: STAT Stitch Deep Dive Podcast Beyond The Bedside · Regular Guy

Opublikowano: 2026-10-05

80/20 Clinical Summary: Renal Failure (AKI vs. CKD) 1. Pathophysiology AKI: Sudden, potentially reversible decline in GFR[1].Prerenal: Decreased perfusion (hypovolemia, shock, HF). Oliguria occurs without tissue damage; reversible with fluids[1][2].Intrarenal: Direct tissue damage, 90% from Acute Tubular Necrosis (ATN) (ischemia, sepsis, nephrotoxins)[2].Postrenal: Mechanical obstruction (BPH, calculi) causing urine reflux[3].CKD: Gradual, irreversible nephron loss (GFR 3 months)[4]. Primary causes: Diabetes (50%), Hypertension (25%)[4]. Stage 5 (ESRD) GFR