Two Lots of the Same Commercial Albumin Differed 5.5-Fold in Endotoxin, and the Immune Response Followed the Endotoxin, Crescent Bioresearch

Podcast: PressCast · Mike Garrett

Opublikowano: 2026-10-20

Investigators at the Medical University of Graz found that the inflammatory activity of commercial research albumins tracked their measured endotoxin content, and that an apparent effect of the protein's own chemistry disappeared once endotoxin was entered as a control variable and tested against. ALBANY, N.Y., Oct. 20, 2026 -- Two containers of the same research-grade albumin, sold under one product number, were found to carry 47.0 and 260.4 picograms of endotoxin per milligram of protein. The gap was 5.5-fold, and the response of human blood cells to the two lots followed it. That observation is one of several in a 2025 study in BBA A...